《精细化工工艺学》

课程基本信息

CourseInformation

课程名称

Course Name

精细化工工艺学

Chemistry and Technologyof Fine Chemicals

开课院部

School

化学工程学院

Collegeof Chemical Engineering

院部代码

School Code

03

负责人

Leader

刘东

Liu Dong

课程团队

Team Members

精细化工

Fine Chemicals

课程编码

Course Code

03225

学分

Credits

3.0

课内学时

Course Hours

48

理论学时

Lecture Hours

48

实验学时

ExperimentHours

0

上机学时

ProgrammingHours

0

实践学时

PracticeHours

0

课外学时

Home Hours

48

适用专业

Audience

应用化学、化学工程与工艺、环境工程

AppliedChemistry, Chemical Engineering and Technology, EnvironmentalEngineering

授课语言

Language ofInstruction

中文

Chinese

先修课程

Prerequisite

有机化学、物理化学、化工原理

Organicchemistry, physical chemistry, Chemical Engineering Principle

课程简介

CourseDescription

本课程是应用化学专业的一门专业课。本课程主要学习精细化学品合成单元过程的化学及工艺学方面的基本理论和知识，包括合成单元反应的基本规律与特点、主要精细化学品的合成工艺。主要内容为：精细化学品合成单元反应的反应历程、反应动力学及热力学分析、反应过程的影响因素、分离过程的影响因素分析、主要精细化学品合成工艺、不同工艺路线的特点以及技术经济比较。通过本课程的学习，掌握精细化学品生产、设计、科研所必须的基本理论、专业知识和实际技能。

Thiscourse is a professional course for applied chemistry. Thiscourse focuses on the basic theory and knowledge of chemical andtechnological of fine chemical synthesis processes unit,including the basic laws and characteristics of syntheticreactions, and the synthetic technology of main fine chemicals.The main contents are as follows: reaction process, reactionkinetics and thermodynamics of fine chemical synthesis unit,factors of reaction process, factors of separation process,synthetic technology of main fine chemicals, characteristics ofdifferent processes and analysis of techno-economic. Through thiscourse, students can grasp the theoretical foundation,professional knowledge and practical skills for working on theproduction, design, research and development of the finechemicals.

课程教学大纲

Course Syllabus

课程目标

LearningOutcomes

课程目标

毕业要求指标点

目标1：掌握精细化学品合成单元反应的基本规律与特点，包括反应历程、反应动力学及热力学分析、反应过程的影响因素、分离过程的影响因素分析。

1.4

目标2：了解并掌握主要精细化学品合成工艺、不同工艺路线的特点以及技术经济比较。

1.4

目标3：掌握从事精细化工生产、设计、科研所必须的基础理论、专业知识和实际技能。

1.4，2.3

目标4：了解国内外精细化工领域的成果和最新进展。

1.4，4.2

LearningOutcomes

MajorObjectives

Outcomes 1: Requirestudents to grasp the basic laws and characteristics of thesynthesis unit reaction of fine chemicals, including reactionprocess, reaction kinetics and thermodynamic analysis, theinfluencing factors of the reaction process, and the influencefactors of the separation process.

1.4

Outcomes 2: Requirestudents to grasp the synthesis process of main fine chemicals,characteristics of different processes and analysis oftechno-economic.

1.4

Outcomes 3: Requirestudents to grasp the theoretical foundation, professionalknowledge and practical skills for working on the production,design, research and development of the fine chemicals.

1.4，2.3

Outcomes 4: Requirestudents to know the latest developments on fine chemicalindustry.

1.4，4.2

教学内容

Topics

第一章绪论（共4学时）

本章重点难点：精细化学品的概念与分类、精细化学品与精细化工的特点、精细有机合成的原料、精细有机合成反应特点。

1.1精细化学品与精细化工

精细化工的概念与范畴、精细化学品的分类、精细化学品与精细化工的特点、精细化工发展概况。

1.2合成路线与反应特点                                                

有机合成原料路线及其展望、有机合成系列产品与加工路线、精细有机合成反应特点概述。

第二章精细有机合成的理论基础    （共2学时）

本章重点难点：反应试剂的概念与分类、反应机理

2.1反应试剂的分类、亲电取代反应、 亲核取代反应、消除反应、游离基反应、加成反应和重排反应    

第三章 精细有机合成的工艺学基础    （共3学时）
本章重点难点：化学计量学的基本概念、溶剂效应、相转移催化、均相配位催化

3.1化学计量学                           

3.2精细有机合成中的溶剂效应           

3.3相转移催化                           

3.4均相配位催化                         

第四章 卤化   （共3学时）

本章重点难点：各类卤化反应特点、工艺特点，产物应用

4.1概述                          

4.2芳环上的取代卤化                                                        

4.3脂烃及芳环侧链的取代卤化                                       

4.4加成卤化和置换卤化                                            

第五章 磺化和硫酸化      （共4学时）

本章重点难点：芳香族磺化与脂肪烃磺化反应特点、工艺特点，磺酸盐与硫酸酯盐产物的区别及应用

5.1磺化概述                                                        

5.2芳香族磺化                                                     

5.3脂肪烃的磺化                                                     

5.4醇和烯烃的硫酸化                                                

第六章 硝化及亚硝化    （共3学时）

本章重点难点：硝化与亚硝化质点及形成条件、硝化与及亚硝化反应特点、混酸硝化、分离特点

6.1硝化概述                              

6.2理论解释                                                     

6.3影响因素                                                   

6.4混酸硝化                                                      

6.5硝化异构产物的分离                                

6.6硝基苯的生产                                              

6.7其它实例                                                     

6.8亚硝化                                                     

第七章 氢化和还原       （共3学时）

本章重点难点：催化氢化的特点、各类还原方法区别及应用

7.1概述

7.2催化氢化                                                    

7.3在电解质溶液中用铁屑还原                                      

7.4锌粉还原                                                      

7.5含硫化合物还原                                                

7.6金属复氢化合物还原                                            

7.7其它还原方法                                                 

第八章 重氮化和重氮基的转化  （共3学时）

本章重点难点：重氮化反应的特点、偶合反应的特点及应用、放出氮的重氮基转化反应特点及应用

8.1概述                                                    

8.2重氮化反应                                                       

8.3保留氮的重氮基转化反应                                         

8.4放出氮的重氮基转化反应                                            

第九章 氨解和胺化    （共3学时）

本章重点难点：氨基化反应的特点、脂肪胺的制备方法及特点、芳香胺的制备方法及特点     

9.1概述

9.2氨基化剂（氨解和胺化所用的反应剂）                             

9.3醇羟基的氨解                                                  

9.4羰基化合物的胺化氢化                                         

9.5环氧烷类的加成胺化                                          

9.6脂族卤素衍生物的氨解                                          

9.7芳环上卤基的氨解                                       

9.8芳环上羟基的氨解                                              

9.9芳环上磺基的氨解

9.10芳环上氢的直接胺化                                           

第十章 烃化  （共3学时）

本章重点难点：烃化反应的类别、反应机理与特点、各类烃化方法及应用

10.1概述                                                   

10.2N－烃化                                                     

10.3O－烃化                                                        

10.4芳环上的C－烃化                                                  

第十一章 酰化      （共3学时）

本章重点难点：酰化反应的类别、反应机理与特点、各类酰化方法及应用

11.1概述                                                         

11.2N－酰化                                                       

11.3O－酰化                                                       

11.4C－酰化                                                         

第十二章 氧化     （共3学时）

本章重点难点：氧化反应机理及特点、各类氧化方法及应用

12.1概述                                                        

12.2空气液相氧化                                                    

12.3空气的气固相接触催化氧化                                    

12.4化学氧化                                                    

第十三章 水解      （共3学时）

本章重点难点：水解反应的类别、反应机理与特点、各类水解方法及应用

13.1概述                                                  

13.2脂链上卤基的水解                                              

13.3芳环上卤基的水解                                            

13.4芳磺酸及其盐类的水解                                              

13.5芳环上硝基的水解                                   

13.6芳环上氨基的水解                                           

13.7酯类的水解                                           

13.8碳水化合物的水解                                             

第十四章 缩合   （共2学时）

本章重点难点：缩合反应机理、缩合方法及应用

14.1概述                                                     

14.2醛醇缩合反应                                                  

14.3羧酸及其衍生物的缩合                                               

第十五章 环合    （共3学时）

本章重点难点：环合反应的特点、分子内环合、分子间多步环合、起始原料的选择

15.1概述

15.2形成六元碳环的环合反应                        

15.3形成含一个氧原子的杂环的环合反应              

15.4形成含一个氮原子的杂环的环合反应             

15.5形成含两个氮原子的杂环的环合反应              

15.6三聚氰酰氯的制备                              

15.7形成含一个氮原子和一个硫原子的杂环的环合反应

第十六章 聚合    （共3学时）

本章重点难点：聚合反应机理、各类聚合物的制备方法及特点

16.1概述                                                           

16.2缩合聚合                                                      

16.3加聚反应                                                       

16.4共聚反应                                                       

16.5聚合物的化学反应                                               

Chapter1 Introduction (4 Class Hours)

Emphasisand difficulties: the definition and classification of finechemicals, the characteristics of fine chemicals and finechemical industry, the raw material of fine organic synthesis,the characteristics of fine organic synthesis reaction

§1.1Fine chemicals and fine chemical industry

Thedefinition and category of fine chemicals, the classification offine chemical industry, the characteristics of fine chemicals andfine chemical industry, the development situation of finechemicals.

§1.2Synthetic route and reaction characteristics

Theroute and prospect of the material for organic synthesis, theproduct and processing route of organic synthesis series, thecharacteristics situation of fine organic synthesis reaction.

Chapter2 The theoretical basis of fine organic synthesis (2 Class Hours)

Emphasisand difficulties: the definition and classification of reactionreagent and its reaction mechanism

§2.1The definition of reaction reagent, electrophilic substitutionreaction, nucleophilic substitution reaction, eliminationreaction, free radical reaction , addition reaction andrearrangement reaction.

Chapter3 The technological basis of fine organic synthesis (3 ClassHours)

Emphasisand difficulties: the basic definition of chemometrics, solventeffect, phase transfer catalysis, homogeneous coordinationcatalysis

§3.1Chemometrics

§3.2Solvent Effect of fine Organic Synthesis

§3.3Phase transfer catalysis

§3.4Homogeneous coordination catalysis

Chapter4 Halogenation (3 Class Hours)

Emphasisand difficulties: the characteristics of various halogenationsand their technology characteristics, the applications of product

§4.1Introduction

§4.2Substituted halogenation of aromatic rings

§4.3Substituted halogenation of aliphatic hydrocarbon and aromaticring side chains

§4.4Addition halogenation and replacement halogenation

Chapter5 Sulfonation and sulfation (4 Class Hours)

Emphasisand difficulties: the reaction and technology characteristics ofaromatic sulfonation and aliphatic hydrocarbon sulfonationreaction, the difference and application of sulfonate and sulfatesalt products

§5.1Introduction of sulfonation

§5.2Aromatic sulfonation

§5.3Sulfonation of aliphatic hydrocarbons

§5.4Sulfation of alcohol and alkene

Chapter6 Nitration and nitrosation (3 Class Hours)

Emphasisand difficulties: the mass point and formation conditions ofnitration and nitrosation, the reaction characteristics ofnitration and nitrosation, nitration of mixed acid, thecharacteristics of separation

§6.1Introduction of nitration

§6.2Theoretical explanation

§6.3Influencing factors

§6.4Nitration of mixed acid

§6.5Separation of nitrification isomer products

§6.6Production of nitrobenzene

§6.7Other examples

§6.8Nitrosation

Chapter7 Hydrogenation and Reduction (3 Class Hours)

Emphasisand difficulties: the characteristics of catalytic hydrogenation,the difference and application of various reduction methods.

7.1Introduction

7.2Catalytic hydrogenation

7.3Reduction with iron scrap in the electrolyte solution

7.4Reduction with zinc powder

7.5Reduction with the sulfur compounds

7.6Reduction with the metal hydrogen compounds

7.7Other reduction methods

Chapter8 The diazotization and diazo conversion (3 Class Hours)

Emphasisand difficulties: the characteristics of diazotization reaction,the characteristics and application of coupling reaction, and thecharacteristics and application of the released nitrogen diazoconversion reactions

8.1Introduction

8.2Diazotization reaction

8.3Reserved nitrogen diazo conversion reactions

8.4Released nitrogen diazo conversion reactions

Chapter9 The ammonia and amination (3 Class Hours)

Emphasisand difficulties: the characteristics of amination reaction, thepreparation and characteristics of fatty amines and thepreparation and characteristics of aromatic amines

9.1Introduction

9.2Aminizing agent (reactants used in ammonolysis and amination)

9.3Ammonolysis of alcoholic hydroxyl groups

9.4Amination Hydroamination of carbonyl compounds

9.5Addition amination of alkylene oxide

9.6Ammonolysis of aliphatic halogen derivatives

9.7Ammonolysis of halo groups on aromatic rings

9.8Ammonolysis of hydroxyl groups on aromatic rings

9.9Ammonolysis of sulfo groups on aromatic rings

9.10Direct amination of hydrogen on aromatic rings

Chapter10 Hydrocarbonation (3 Class Hours)

Emphasisand difficulties: classification of hydrocarbonation reactions,reaction mechanism and characteristics of hydrocarbonation,various methods of hydrocarbonation and their applications

10.1Introduction

10.2N-hydrocarbonation

10.3O-hydrocarbonation

10.4C- hydrocarbonation on aromatic rings

Chapter11 Acylation (3 Class Hours)

Emphasisand difficulties: classification of acylation reactions, reactionmechanisms and characteristics of acylation reactions, variousmethods of acylation and their applications

11.1Introduction

11.2N-acylation

11.3O-acylation

11.4C-acylation

Chapter12 Oxidation (3 Class Hours)

Emphasisand difficulties: the mechanism and characteristics of oxidation,various methods of oxidation and their applications

12.1Overview

12.2Liquid-phase oxidation with air

12.3Gas-solid phase contact catalytic oxidation with air

12.4Chemical oxidation

Chapter13 Hydrolysis (3 Class Hours)

Emphasisand difficulties: the classification, reaction mechanism andcharacteristics of hydrolysis reaction, various methods ofhydrolysis and their applications

§13.1Introduction

§13.2Hydrolysis of halogen groups on fatty chains

§13.3Hydrolysis of halogen groups on the aromatic rings

§13.4Hydrolysis of aryl sulfonic acids and their salts

§13.5Hydrolysis of nitro groups on aromatic rings

§13.6Hydrolysis of amino groups on aromatic rings

§13.7Hydrolysis of esters

§13.8Hydrolysis of carbohydrate

Chapter14 Condensation (2 class hours)

Emphasisand difficulties: mechanism of condensation reaction, methods ofcondensation and their applications

§14.1Introduction

§14.2Condensation of aldol

§14.3Condensation of carboxylic acids and their derivatives

Chapter15 Cyclization (3 class hours)

Emphasisand difficulties: the characteristics of cyclization reaction,intramolecular cyclization reaction, intermolecular multi-stepcyclization reaction, the choice of the starting material

§15.1Introduction

§15.2Cyclization reaction for forming six carbon ring

§15.3Cyclization reaction for forming a heterocycle containing anoxygen atom

§15.4Cyclization reaction for forming a heterocycle containing anitrogen atom

§15.5Cyclization reaction for forming a heterocycle containing twonitrogen atoms

§15.6Preparation of cyanuric chloride

§15.7Cyclization reaction for forming a heterocycle containing anitrogen atom and a sulfur atom

Chapter16 Aggregation (3 class hours)

Emphasisand difficulties: polymerization mechanism, preparation methodsand characteristics of various polymers

§16.1Introduction

§16.2Condensation polymerization

§16.3Addition polymerization reaction

§16.4Copolymerization reaction

§16.5Chemical Reaction of Polymers

教学进度及要求

ClassSchedule & Requirements

内容

课内

学时

教学方式

课外

学时

课外环节

课程目标

1.1

2

讲授

2

自学

4

1.2

2

讲授

2

自学+作业

4

2.1

2

讲授

2

自学

1

3.1

0.5

讲授

0.5

自学

3

3.2

1

讲授

1

自学

3

3.3

0.5

讲授

0.5

自学

3

3.4

1

讲授

1

自学+作业

3

4.1

1

讲授

1

自学

3

4.2

讲授

自学

1，2，3

4.3

1

讲授

1

自学

1，2，3

4.4

1

讲授

1

自学+作业

1，2，3

5.1

0.5

讲授

0.5

自学

4

5.2

1.5

讲授

1.5

自学

1，2，3

5.3

1

讲授

1

自学

1，2，3

5.4

1

讲授

1

自学+作业

1，2，3

6.1

0.5

讲授

0.5

自学

4

6.2

讲授

自学

1，,3

6.3

0.5

讲授

0.5

自学

1

6.4

0.5

讲授

0.5

自学

1，2，3

6.5

0.5

讲授

0.5

自学

1

6.6

0.5

讲授

0.5

自学

2，3

6.7

0.5

讲授

0.5

自学

2，,3

6.8

讲授

自学+作业

2，3

7.1

0.5

讲授

0.5

自学

4

7.2

讲授

自学

1，2，3

7.3

0.5

讲授

0.5

自学

1，2，3

7.4

0.5

讲授

0.5

自学

1，2，3

7.5

0.5

讲授

0.5

自学

1，2，3

7.6

0.5

讲授

0.5

自学

1，2，3

7.7

0.5

讨论

0.5

自学+作业

1，2，3

8.1

1

讲授

1

自学

4

8.2

讲授

自学

1，3

8.3

1

讲授

1

自学

1，3

8.4

1

讲授

1

自学

1，3

9.1

0.5

讲授

0.5

自学

4

9.2

讲授

自学

1

9.3

0.5

讲授

0.5

自学

1，3

9.4

0.5

讲授

0.5

自学

1，3

9.5

讲授

自学

1，3

9.6

0.5

讲授

0.5

自学

1，3

9.7

0.5

讲授

0.5

自学

1，3

9.8

讲授

自学

1，3

9.9

0.5

讲授

0.5

自学

1，3

9.10

讲授

自学+作业

1，3

10.1

1

讲授

1

自学

4

10.2

讲授

自学

1，3

10.3

1

讲授

1

自学

1，3

10.4

1

讲授

1

自学

1，2，3

11.1

1

讲授

1

自学

4

11.2

讲授

自学

1，3

11.3

1

讲授

1

自学

1，3

11.4

1

讲授

1

自学+作业

1，3

12.1

0.5

讲授

0.5

自学

4

12.2

1

讲授

1

自学

1，2，3

12.3

1

讲授

1

自学

1，2，3

12.4

0.5

讲授

0.5

自学+作业

1，3

13.1

0.5

讲授

0.5

自学

4

13.2

讲授

自学

1，3

13.3

0.5

讲授

0.5

自学

1，3

13.4

1

讲授

1

自学

1，3

13.5

0.5

讲授

0.5

自学

1，3

13.6

讲授

自学

1，3

13.7

0.5

讲授

0.5

自学

1，3

13.8

讲授

自学+作业

1，3

14.1

1

讲授

1

自学

4

14.2

讲授

自学

1，3

14.3

1

讲授

1

自学

1，3

15.1

0.5

讲授

0.5

自学

4

15.2

讲授

自学

1，3

15.3

0.5

讲授

0.5

自学

1，3

15.4

0.5

讲授

0.5

自学

1，3

15.5

0.5

讲授

0.5

自学

1，3

15.6

0.5

讲授

0.5

自学

2，3

15.7

0.5

讲授

0.5

自学+作业

1，3

16.1

1

讲授

1

自学

4

16.2

讲授

自学

1，3

16.3

1

讲授

1

自学

1，3

16.4

0.5

讲授

0.5

自学

1，3

16.5

0.5

讨论

0.5

自学

1，3

Topics

Course

Hours

TeachingMethods

Home

Hours

Assignment

Outcomes

1.1

2

Teaching

2

Reading

4

1.2

2

Teaching

2

Reading

4

2.1

1

Teaching

1

Reading

1

3.1

0.5

Teaching

0.5

Reading

3

3.2

1

Teaching

1

Reading

3

3.3

0.5

Teaching

0.5

Reading

3

3.4

1

Teaching

1

Reading &Homework

3

4.1

1

Teaching

1

Reading

3

4.2

Teaching

Reading

1，2，3

4.3

1

Teaching

1

Reading

1，2，3

4.4

1

Teaching

1

Reading &Homework

1，2，3

5.1

0.5

Teaching

0.5

Reading

4

5.2

1.5

Teaching

1.5

Reading

1，2，3

5.3

1

Teaching

1

Reading

1，2，3

5.4

1

Teaching

1

Reading &Homework

1，2，3

6.1

0.5

Teaching

0.5

Reading

4

6.2

Teaching

Reading

1，,3

6.3

0.5

Teaching

0.5

Reading

1

6.4

0.5

Teaching

0.5

Reading

1，2，3

6.5

0.5

Teaching

0.5

Reading

1

6.6

0.5

Teaching

0.5

Reading

2，3

6.7

0.5

Teaching

0.5

Reading

2，,3

6.8

Teaching

Reading &Homework

2，3

7.1

0.5

Teaching

0.5

Reading

4

7.2

Teaching

Reading

1，2，3

7.3

0.5

Teaching

0.5

Reading

1，2，3

7.4

0.5

Teaching

0.5

Reading

1，2，3

7.5

0.5

Teaching

0.5

Reading

1，2，3

7.6

0.5

Teaching

0.5

Reading

1，2，3

7.7

0.5

Discussing

0.5

Reading &Homework

1，2，3

8.1

1

Teaching

1

Reading

4

8.2

Teaching

Reading

1，3

8.3

1

Teaching

1

Reading

1，3

8.4

1

Teaching

1

Reading

1，3

9.1

0.5

Teaching

0.5

Reading

4

9.2

Teaching

Reading

1

9.3

0.5

Teaching

0.5

Reading

1，3

9.4

0.5

Teaching

0.5

Reading

1，3

9.5

Teaching

Reading

1，3

9.6

0.5

Teaching

0.5

Reading

1，3

9.7

0.5

Teaching

0.5

Reading

1，3

9.8

Teaching

Reading

1，3

9.9

0.5

Teaching

0.5

Reading

1，3

9.10

Teaching

Reading &Homework

1，3

10.1

1

Teaching

1

Reading

4

10.2

Teaching

Reading

1，3

10.3

1

Teaching

1

Reading

1，3

10.4

1

Teaching

1

Reading

1，2，3

11.1

1

Teaching

1

Reading

4

11.2

Teaching

Reading

1，3

11.3

1

Teaching

1

Reading

1，3

11.4

1

Teaching

1

Reading &Homework

1，3

12.1

0.5

Teaching

0.5

Reading

4

12.2

1

Teaching

1

Reading

1，2，3

12.3

1

Teaching

1

Reading

1，2，3

12.4

0.5

Teaching

0.5

Reading &Homework

1，3

13.1

0.5

Teaching

0.5

Reading

4

13.2

Teaching

Reading

1，3

13.3

0.5

Teaching

0.5

Reading

1，3

13.4

1

Teaching

1

Reading

1，3

13.5

0.5

Teaching

0.5

Reading

1，3

13.6

Teaching

Reading

1，3

13.7

0.5

Teaching

0.5

Reading

1，3

13.8

Teaching

Reading &Homework

1，3

14.1

1

Teaching

1

Reading

4

14.2

Teaching

Reading

1，3

14.3

1

Teaching

1

Reading

1，3

15.1

0.5

Teaching

0.5

Reading

4

15.2

Teaching

Reading

1，3

15.3

0.5

Teaching

0.5

Reading

1，3

15.4

0.5

Teaching

0.5

Reading

1，3

15.5

0.5

Teaching

0.5

Reading

1，3

15.6

0.5

Teaching

0.5

Reading

2，3

15.7

0.5

Teaching

0.5

Reading &Homework

1，3

16.1

1

Teaching

1

Reading

4

16.2

Teaching

Reading

1，3

16.3

1

Teaching

1

Reading

1，3

16.4

0.5

Teaching

0.5

Reading

1，3

16.5

0.5

Teaching

0.5

Reading

1，3

考核方式

Grading

评价环节

比例

环节1：课堂出勤

10%

环节2：课堂讨论

10%

环节3：课程作业

10%

环节4：考试

70%

Evaluation

Percentage

Evaluation1：Attendance

10%

Evaluation2：Discussion

10%

Evaluation3：Homework

10%

Evaluation4：Test

70%

教材及参考资料

Textbooks &Other Materials

1．《精细有机合成化学及工艺学》（第二版），唐培堃主编，天津大学出版社，2002年9月。化工部优秀教材一等奖。

2．《精细化工产品合成原理》(第二版)，姚蒙正、程侣柏、王家儒，中国石化出版社，2000年。

3.《精细有机合成原理与工艺》，陈金龙主编，中国轻工业出版社，1992年4月。

4.《精细有机合成单元反应》，张铸勇主编，华东化工学院出版社，1990年6月。

1.Tang Peikun, FineOrganic Synthesis Chemistry and Technology (2nd Edition), TianjinUniversity Press, 2002.

2.Yao Mengzheng, Cheng Lvbai, Wang Jiaru, SyntheticPrinciple of Fine Chemical Products (2nd Edition), ChinaPetrochemical Press, 2000.

3.Chen Jinlong, Principleand Process of Fine Organic Synthesis, ChinaLight Industry Press, 1992.

2. Zhangzhuyong, Unitreaction of Fine Organic Synthesis, EastChina Institute of Chemical Technology Press, 1992.

其它

More

备注

Notes

大纲执笔人

Author

南国枝，罗辉

Nan Guozhi,Luo Hui

审核人(系/教研室主任)

Approved by

刘东

Luo Dong